{"id":1403,"date":"2026-03-11T13:43:30","date_gmt":"2026-03-11T12:43:30","guid":{"rendered":"https:\/\/uniteid.fr\/?p=1403"},"modified":"2026-04-07T17:17:24","modified_gmt":"2026-04-07T15:17:24","slug":"etude-des-mecanismes-dantibiotolerance","status":"publish","type":"post","link":"https:\/\/uniteid.fr\/en\/etude-des-mecanismes-dantibiotolerance\/","title":{"rendered":"Study of antibiotic tolerance and persistence mechanisms in enterobacteria"},"content":{"rendered":"<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li class=\"has-medium-font-size\">Doctoral student : Lucile BILLET<\/li>\n\n\n\n<li class=\"has-medium-font-size\">Manager: Julien VAUBOURGEIX<\/li>\n\n\n\n<li class=\"has-medium-font-size\">Laboratory: Institute for Digestive Health Research - IRSD<\/li>\n\n\n\n<li class=\"has-medium-font-size\">Dates: October 1, 2025 to September 30, 2028<\/li>\n<\/ul>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">This project directly addresses the threat of emerging infectious diseases by studying antibiotic-resistant Escherichia coli strains associated with difficult-to-treat infections. Tolerance and persistence are clinical challenges: they contribute to longer treatment times and higher recurrence rates, and promote the development of resistance. The project will study Escherichia coli strains resistant to third-generation cephalosporins and carbapenems, two priority pathogens on the World Health Organization's (WHO) Global Priority List 2024.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>","protected":false},"excerpt":{"rendered":"<p>Ce projet aborde directement la menace que repr\u00e9sentent les maladies infectieuses \u00e9mergentes en \u00e9tudiant les souches d\u2019 Escherichia coli r\u00e9sistantes aux antibiotiques et associ\u00e9es \u00e0 des infections difficiles \u00e0 traiter. La tol\u00e9rance et la persistance constituent des d\u00e9fis cliniques : elles contribuent \u00e0 prolonger la dur\u00e9e des traitements et \u00e0 augmenter les taux de r\u00e9cidive, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":142,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[20],"tags":[],"class_list":["post-1403","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-these"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u00c9tude des m\u00e9canismes d&#039;antibiotol\u00e9rance et de persistance chez les ent\u00e9robact\u00e9ries - UNITEID Graduate school<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/uniteid.fr\/en\/etude-des-mecanismes-dantibiotolerance\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00c9tude des m\u00e9canismes d&#039;antibiotol\u00e9rance et de persistance chez les ent\u00e9robact\u00e9ries - UNITEID Graduate school\" \/>\n<meta property=\"og:description\" content=\"Ce projet aborde directement la menace que repr\u00e9sentent les maladies infectieuses \u00e9mergentes en \u00e9tudiant les souches d\u2019 Escherichia coli r\u00e9sistantes aux antibiotiques et associ\u00e9es \u00e0 des infections difficiles \u00e0 traiter. 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